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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYST3 All Species: 9.7
Human Site: S374 Identified Species: 23.7
UniProt: Q92794 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92794 NP_001092882.1 2004 225028 S374 K I T L S S Q S A S S S S E E
Chimpanzee Pan troglodytes XP_519734 1952 219524 S374 K I T L S S Q S A S S S S S E
Rhesus Macaque Macaca mulatta XP_001094798 1531 171769 S51 N W I S T F T S G I R L E E Q
Dog Lupus familis XP_864262 1903 213436 L395 G K D S S S R L A V T D P T R
Cat Felis silvestris
Mouse Mus musculus Q8BZ21 2003 224900 Q373 R K I T V S S Q S A S S S E E
Rat Rattus norvegicus Q5TKR9 1998 223312 Q373 R K I T V S S Q S A S S S E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509744 2001 224966 Q374 R K I T L S S Q S A S S S E E
Chicken Gallus gallus XP_424402 1981 222543 S373 K R K I T L S S Q S A S S E G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001116784 2246 246681 S400 S S P H S S S S S S C E G Y P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786050 3082 341137 G387 Q G K Q D S Q G S S D G T G I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97 74 52.9 N.A. 89.2 88.9 N.A. 88.6 84.4 N.A. 53.8 N.A. N.A. N.A. N.A. 26.9
Protein Similarity: 100 97.1 75.2 66.5 N.A. 93.6 93 N.A. 93.2 89.9 N.A. 64.7 N.A. N.A. N.A. N.A. 41.1
P-Site Identity: 100 93.3 13.3 20 N.A. 40 40 N.A. 40 40 N.A. 26.6 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 93.3 26.6 33.3 N.A. 60 60 N.A. 60 60 N.A. 33.3 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 30 30 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 0 10 0 10 0 0 0 0 0 10 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 10 10 60 50 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 0 0 0 0 0 10 10 0 0 10 10 10 10 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 20 40 10 0 0 0 0 0 10 0 0 0 0 10 % I
% Lys: 30 40 20 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 20 10 10 0 10 0 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 10 % P
% Gln: 10 0 0 10 0 0 30 30 10 0 0 0 0 0 10 % Q
% Arg: 30 10 0 0 0 0 10 0 0 0 10 0 0 0 10 % R
% Ser: 10 10 0 20 40 80 50 50 50 50 50 60 60 10 0 % S
% Thr: 0 0 20 30 20 0 10 0 0 0 10 0 10 10 0 % T
% Val: 0 0 0 0 20 0 0 0 0 10 0 0 0 0 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _